Biology Research Scientist Job at Amber Bio, San Francisco, CA

QUk2VG9tdEtCRCtDVC9VZ0JSeld6MHY3OXc9PQ==
  • Amber Bio
  • San Francisco, CA

Job Description

Amber Bio is a biotechnology company pioneering new gene editing modalities using multi-kilobase edits to reach previously undruggable patient populations. Founded by pioneers in the CRISPR field from leading institutions for gene editing research, the company is developing a first-of-its-kind RNA writing platform that can correct thousands of bases at once, thereby correcting genetic mutations safely and reversibly. Multiple openings are available on a rapidly growing team. As an early team member, you will have the opportunity to contribute to strategic planning and future hiring. If you are interested in building a new frontier in genetic medicine, please apply through LinkedIn.

If you are a skilled Computational Biologist or ML Scientist with a passion for applying machine learning approaches to (one of: model/design/engineer) biological sequences, we encourage you to apply and join our innovative team.

Job Description: Computational Biologist / ML Scientist (Bioarchitect)

Responsibilities include:

  • Implement state of the art methods to predict RNA and protein function from sequence.
  • Analyze and preprocess experimental data, including DNA, RNA, and protein sequences, high throughput screening data and structural data for model training and validation.
  • Plan and execute machine learning experiments, and set milestones and timelines to achieve research objectives.
  • Collaborate with wet lab scientists to align ML experiments and integrate model insights into the design process
  • Fine-tune models using custom datasets and external resources to achieve high predictive performance.
  • Collaborate with gene editing and molecular biology experts to integrate model insights into the design process.
  • Stay updated with the latest advancements in machine learning techniques, RNA/protein structure prediction, and gene editing technologies.
  • Publish results in relevant conferences and peer-reviewed journals.
  • Design, build, and maintain computational pipelines to process, analyze, and interpret next-generation sequencing (NGS) data, including variant calling and differential expression analysis.

Qualifications:

  • Ph.D. in Computer Science, Bioinformatics, Computational Biology, Molecular Biology, or related fields. Strong academic background in machine learning and molecular biology is preferred.
  • Minimum of 2 years of practical experience in developing machine learning models, with a focus on RNA and protein structure prediction, acquired during PhD studies or a post-graduate role.
  • Proven track record of addressing high impact questions in biology using statistical and machine learning techniques.
  • Understanding of gene editing techniques, such as CRISPR-Cas9.
  • Experience with RNA and protein structure prediction tools and databases (e.g., Rosetta, RNAfold, PyRosetta, AlphaFold).
  • Proficiency in Python and PyTorch / TensorFlow and other bioinformatics tools.
  • Excellent communication skills and the ability to collaborate effectively with technical and non-technical teams.
  • Strong analytical skills with the ability to design creative solutions for complex molecular challenges.

Preference will be given to those who display:

  • High motivation, with a strong work ethic and dedication to generating impact.
  • Long-term personal vision with defined career goals.
  • High EQ with team-oriented thinking.

If you have a passion for advancing gene editing technologies and desire to be part of a pioneering biotech company, we encourage you to apply and join our ambitious team.

Amber Bio is an equal-opportunity employer and encourages applications from candidates of diverse backgrounds. We value diversity and are committed to creating an inclusive and supportive work environment for all employees.

Job Tags

Similar Jobs

Ernst & Young

US - CBS - ESS - Admin Services - Executive Assistant Admin Advanced FY26 Job at Ernst & Young

At EY, were all in to shape your future with confidence. Well help you succeed in a globally connected powerhouse of diverse teams and take your career wherever you want it to go. Join EY and help to build a better working world. As part of our Enterprise Support...

MaxCyte, Inc

Data Scientist Job at MaxCyte, Inc

 ...Description: We are looking for a highly motivated Data Scientist to join our team, contributing to the development of innovative software and assays designed to assess the off-target safety profiles of CRISPR-based gene editing systems, The ideal candidate will bring... 

Addition Management

Executive Sous Chef Job at Addition Management

 ...Growing Hospitality Services provider is seeking an Executive Sous Chef to join their team! Responsibilities: Responsible for food preparation and expediting. Maintain a clean and organized kitchen environment Maintain consistency in food quality standards.... 

Ricoh USA, Inc.

Delivery Driver Job at Ricoh USA, Inc.

 ...The Delivery & Set-Up Driver is tasked with the efficient and high-quality pick-up, relocation, and delivery of office equipment in a safe manner. This role may involve the installation and networking of equipment upon delivery to customers. The professionalism and quality... 

Optomi

Junior Product Owner Job at Optomi

 ...within the telecommunications industry, is seeking an experienced Junior Product Owner for their Long Island City, NY; Plano, TX; Bethpage, NY...  ...user stories and acceptance criteria. Triage and manage incoming bugs, feature requests, and support tickets from internal...